Preheat the air fryer to 360F / 182C.
Gather three small bowls. Combine the flour, salt, and chili powder in one. In another combine the egg and the buttermilk. In the last bowl, combine the panko, Franks Red Hot Buffalo Ranch seasoning, and the Italian seasoning.
Peel, de-vein and remove the tails from one pound of shrimp.
Start by coating the shrimp in the flour mixture, then dip in the egg mixture, and lastly coat with the Panko seasoning.
Shake off excess crumbs and place half of the shrimp in the air fryer basket and coat with cooking spray.
Cook about 8 minutes, until crispy and golden brown, turning once halfway through.
Remove from air fryer, set aside, and then repeat with the remaining shrimp.